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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T18312 | Mc-MMAE | Maleimidocaproyl-monomethylauristatin E | Microtubule Associated |
Mc-MMAE (Maleimidocaproyl-monomethylauristatin E) is a drug-linker conjugate for ADC. Mc-MMAE is a maleimidocaproyl-conjugated monomethyl auristatin E, which is a potent tubulin inhibitor. | |||
T39164 | MC-betaglucuronide-MMAE-1 | ||
MC-betaglucuronide-MMAE-1 is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADCs), employing MMAE (a tubulin polymerization inhibitor) connected through the cleavable ADC linker MC-betaglucuronide... | |||
T4232 | VCMMAE | mc-vc-PAB-MMAE | Microtubule Associated |
VCMMAE (mc-vc-PAB-MMAE) is a drug-linker conjugate for ADC with potent antitumor activity. | |||
T81835 | MC-betaglucuronide-MMAE-2 | ||
MC-betaglucuronide-MMAE-2 is an ADC (antibody-drug conjugate) agent-linker conjugate that exhibits potent antitumor activity; it consists of MMAE (a tubulin polymerization inhibitor) connected through the cleavable linke... | |||
T77853 | MC-VA-PABC-MMAE | ||
MC-VA-PABC-MMAE is a conjugate consisting of the ADC linker peptide MC-VA-PABC and the cytotoxic agent monomethyl auristatin E (MMAE), a powerful inhibitor of tubulin polymerization [1] [2]. This compound serves as an ag... | |||
T79206 | MC-EVCit-PAB-MMAE | ||
MC-EVCit-PAB-MMAE (Linker-Payload 11), a conjugate utilized in antibody-drug conjugates (ADCs), comprises the MC-EVCit-PAB linker attached to the powerful tubulin polymerization inhibitor MMAE [1]. | |||
T79039 | GGGDTDTC-Mc-vc-PAB-MMAE | ||
GGGDTDTC-Mc-vc-PAB-MMAE is a drug-linker conjugate for antibody-drug conjugates (ADCs), incorporating the tubulin inhibitor monomethyl auristatin E (MMAE) as the cytotoxic component [1]. | |||
T77839 | Bi-Mc-VC-PAB-MMAE | ||
Bi-Mc-VC-PAB-MMAE is an agent-linker conjugate for antibody-drug conjugates (ADCs), featuring the linker (Fmoc-Val-Cit-PAB) and the potent tubulin inhibitor (MMAE). | |||
T78521 | Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE | Others | |
Compound S6, Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE, is a potent anticancer agent specifically activated by the tumor microenvironment; it demonstrates efficacy in suppressing tumor growth in mice[1]. | |||
T18321 | Mc-Val-Cit-PAB-Cl | Others | |
Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC5... | |||
T77838 | Telisotuzumab vedotin | ABBV-399 | |
Telisotuzumab vedotin (ABBV-399), an antibody-drug conjugate (ADCs), targets c-Met and comprises the cytotoxic agent Monomethyl Auristatin E (MMAE), the Telisotuzumab antibody, and a cleavable mc-val-cit-PABC linker. Thi... |